Structural decomposition and heterogeneity of commercial lipoteichoic Acid preparations.

Definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives.

The controversy about the immune stimulatory properties of lipoteichoic acid (LTA) from Staphylococcus aureus was solved recently by showing decomposition and inactivation of LTA obtained by conventional purification strategies, as well as pronounced LPS contamination of commercial preparations. By introducing a novel preparation method, the structure of bioactive LTA was elucidated. This struc...

Activation of Mouse Macrophages In Vitro to Acid Contain Endotoxin That Contributes Commercial Preparations of Lipoteichoic

EFFECT OFACID ACTIVATION ON STRUCTURALAND BLEACHING PROPERTIES OFABENTONITE

 A natural bentonite obtained from Khorasan, Iran, was submitted to acid activation with sulphuric acid. Sample aliquots (5gr)were leached with 100 ml H2SO4 solutions of various concentrations (2–7N) at 80±2 oC for 2 hours. X–ray diffraction, chemical analysis, infrared spectroscopy and specific surface area measurements were performed in order to evaluate important structural modifications occ...

Application of Non-Corrosive Acids in Three-Component, One-Pot Synthesis of Commercial Coumarin Dye

The efficiency of HZSM-5 Zeolite, tungestophosphoric acid (H3PW12O40) and tungestosililic acid (H4O40SiW12) were investigated in three-component, one-pot synthesis of coumarin dyes. These green and noncorrosive acids were highly efficient in synthesis of some coumarin dyes in excellent yield during concurrent formation of coumarin and benzimidazole or benzoxazole heterocycles (e.g. C. I. disper...

Binding of streptococcal lipoteichoic acid to the fatty acid binding sites on serum albumin.

The ability of the fatty acid binding sites of serum albumin to bind lipoteichoic acid of Streptococcus pyogenes was investigated. Initial studies indicated that lipoteichoic acid, but not its deacylated deprivative, protected albumin from being denatured by heat (80C for 1 h) and changed its mobility in an electrical field. Albumin covalently linked to agarose beads bound radiolabeled lipoteic...